One possible mechanism for Myocardial infarction(heart attack) with 'normal' coronary arteries (MINCA) is occlusion of the vessel lumen by thrombus(clot) that subsequently lyses rapidly.
Platelet(mico-cells that aid clotting) aggregates have been shown to cause transmural infarction(heart attack) and their half-life is 10-15 minutes. The evidence on hypercoagulable states( increased rate of clotting) is mixed.
The risk of heart attack is above normal in people with raised plasma fibrinogen and plasminogen activator inhibitor(the factors that help normal clotting) . However, for most clotting abnormalities, including the most common inherited thrombophilia, factor V Leiden, there is no consistent link with heart attack.
In reports suggesting some excess risk, this was mainly in people who had other risk factors for coronary artery disease.
Platelet(mico-cells that aid clotting) aggregates have been shown to cause transmural infarction(heart attack) and their half-life is 10-15 minutes. The evidence on hypercoagulable states( increased rate of clotting) is mixed.
The risk of heart attack is above normal in people with raised plasma fibrinogen and plasminogen activator inhibitor(the factors that help normal clotting) . However, for most clotting abnormalities, including the most common inherited thrombophilia, factor V Leiden, there is no consistent link with heart attack.
In reports suggesting some excess risk, this was mainly in people who had other risk factors for coronary artery disease.